National Clinical Cohort Collaborative (N3C) Homepage



By leveraging our collective data resources, unparalleled analytics expertise, and medical insights from expert clinicians, we can synergize discoveries that address this pandemic beyond the sum of our parts. The National COVID Cohort Collaborative (N3C) is a collaboration among the NCATS-supported Clinical and Translational Science Awards (CTSA) Program hubs, the National Center for Data to Health (CD2H), distributed clinical data networks (PCORnet, OHDSI, ACT, TriNetX), and other partner organizations, with overall stewardship by NIH’s National Center for Advancing Translational Sciences (NCATS). The N3C aims to improve the efficiency and accessibility of analyses with COVID-19 clinical data, expand our ability to analyze and understand COVID, and demonstrate a novel approach for collaborative pandemic data sharing.

N3C Education

The mission of the N3C Education Enclave is to provide educators and learners a space to develop and practice the skills needed to analyze real-world data (RWD, e.g., non-clinical trial data, such as from medical records, insurance claims, patient surveys, or census or community datasets). The Education Enclave provides simulated (also known as ‘synthetic’ or notional) datasets to learn on, as well as a series of training tutorials, the Researcher’s Guide to the N3C - a virtual textbook of the concepts and skills needed to study RWD, and access to many of the shared resources available to the broader N3C community.

N3C Cancer

The National Clinical Cohort Collaborative (N3C) Cancer Enclave is part of a broader feasibility testing initiative being done to refine the overall governance, data linkage, and institutional partnership components of N3C. The objective of the Cancer Enclave is to test the feasibility of linking data from multiple sources to generate a comprehensive data enclave.

N3C Renal

Renal blurb